Aims: To review 25 cases of breast hamartoma and discuss the pathological criteria, and the usefulness of imaging modalities, fine needle aspiration cytology (FNAC), and needle core biopsy in the diagnosis. Compared with the peripheral parenchyma, 10 hamartomas (27.8%) showed rapid perfusion mode, 23 (63.9%) showed equal perfusion mode, 24 (66.7%) showed equal enhancement, and 9 (25.0%) showed hyperenhancement. NLM Case contributed by Dr Mark Holland . American Journal of Clinical Pathology, 103 , … Hamartoma is a well circumscribed breast lesion with varying amounts of benign epithelial elements, fibrous tissue, and fat. Hamartomas of the breast. Because Of the 36 breast hamartomas, 30 had heterogeneous echogenicity (83.3%, 30/36) and 28 were without changed posterior echogenicity (77.8%, 28/36). They may be discovered incidentally during imaging studies performed for other reasons. The patient is well 12 months later, without tumor recurrence. In this retrospective analysis, we included 36 breast hamartomas of 36 female patients who had been scheduled for US-guided vacuum-assisted biopsy (VAB) or surgical excision between May 2013 and October 2016. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Mammary Myoid Hamartoma J Med Ultrasound 2005 • Vol 13 • … Breast hamartoma The asymmetric lesion by imaging and the histologic finding of normal breast components supports this diagnosis. Breast hamartoma: Ultrasound, elastosonographic, and contrast-enhanced ultrasound features. 1. Mammography, Ultrasound, Hamartoma, Togo 1. A hamartoma is a benign tumor composed of various tissues, and one of its locations may be the breast. Clipboard, Search History, and several other advanced features are temporarily unavailable. Because it resembles normal breast tissue, the margins are often difficult to delineate. Breast elastography: the technical process and its applications. Would you like email updates of new search results? The diagnosis of hamartoma is normally straightforward, due to an extremely characteristic imaging appearance. However, there are increasing rates of breast hamartoma diagnoses due to the huge surge of usage of breast diagnostic procedures such as ultrasound and mammography. Epub 2016 Jun 24. The pathogenesis is still poorly understood and breast hamartoma is not a well-known disorder, so its diagnosis is underestimated by clinicians and pathologists. Ultrasound is helpful in the evaluation of breast masses that are palpable or present as a mammographic abnormality [1, 2].The echo pattern of breast lesions is categorized as anechoic, hypoechoic, isoechoic, or hyperechoic with reference to the subcutaneous fat in the American College of Radiology (ACR) BI-RADS [].The echogenicity of fat in the breast is at the middle of the gray-scale spectrum. The entity is a well delimited mass composed of dysplastic-appearing mammary tissue admixed to fat. Hamartoma of the breast, an underrecognized breast lesion: A clinicopathologic and radiographic study of 25 cases. Please enable it to take advantage of the complete set of features! Mosby Inc. (2006) ISBN:0323017460. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. These are lesions co[1] n-[1] [2 Hamartomas are tumours formed by a cumuli of various epithelial elements, accounting for less than 5% of benign breast masses. We describe a mammary hamartoma in a man; this is … Breast hamartoma: Unusual radiological presentation. In instances where the hamartoma changes shape or increases in size, a biopsy and surgical removal of the mass may be performed. Hamartoma in breast with ultrasound. 17. Two of these had findings considered classic for hamartoma. Breast hamartoma: Ultrasound, elastosonographic, and contrast-enhanced ultrasound features Gang Liu 1, Zhi Li Wang 2, Meng Ke Zhang 2, Yan He 2, Yuan Liu 2 1 Department of Radiology, Chinese People's Liberation Army General Hospital, Beijing, China 2 Department of Ultrasound, Chinese People's Liberation Army General Hospital, Beijing, China 5. 2-7(6) 2. Please help improve this section by adding citations to reliable sources. All breast hamartomas had an oval-shaped and a circumscribed margin. Conclusions: Aims: 1999;19 Spec No : S11-26. 2016 Sep;71(9):896-904. doi: 10.1016/j.crad.2016.06.104. Of the 36 hamartomas, 30 (83.3%) had heterogeneous echogenicity and 28 (77.8%) displayed no changes in posterior echogenicity. Breast hamartomas, also known as fibroadenolipomas, ... Ultrasound. Chao TC, Chao HH, Chen MF. A simple surgical excision and removal of the entire Hamartoma of breast is normally sufficient treatment for big and symptomatic tumours, but a ‘wait and watch’ approach may be considered for asymptomatic hamartomas. Feder JM, De paredes ES, Hogge JP et-al. The term hamartoma was first coined by Arrigoni et al in 1971, 1 as a well circumscribed breast lesion with varying amounts of benign epithelial elements, fibrous tissue, and fat. Presentation. J Ultrasound … Unable to process the form. The Mammary Hamartoma. All breast hamartomas had an oval shape and a circumscribed margin. Abnormal masses were detected on 12. While these tumors can appear at any age, mammary hamartomas are typically found in … Breast hamartomas most commonly are asymptomatic or present as a painless soft breast lump. We describe a mammary hamartoma in a man; this is the fourth case being reported in the literature.. She was recently controlled with breast ultrasound … Breast hamartoma is a relatively rare entity with an incidence of approximately 0.7% of benign breast masses. Because it resembles normal breast tissue, the margins are often difficult to delineate. They may also present as unilateral breast enlargement without a palpable localized mass 4. Rationale: Mammary hamartoma is a rare benign breast tumor, composed of ducts, lobules, fibers, and adipose tissue. Breast hamartomas, also known as fibroadenolipomas, are benign breast lesions. Sonographic Evaluation of the Breast. Ultrasound (US)-guided vacuum-assisted breast biopsy (VABB) has been reported sufficiently safe in treating many breast benign tumors but remained undefined in mammary hamartoma for its usual underdiagnosis in US. Philip JD, Richard JR, Gordon LL, et al. They typically occur in women older than 35 years of age. All hamartomas appeared with a clear edge on CEUS, and none showed lesion diameter expansion after the injection of contrast. 2006 (22) 33, F Axillary mass 10 Compatible with the diagnosis of a voluminous nodule NP NP NP Hamartoma NP No (2-year follow-up) Ruiz-Tovar et al., 2006 (23) 43.2 (mean), F, 8 cases Lump (all) 7.25 (mean) Heterogeneous mass with hypoechogenic areas [ncbi.nlm.nih.gov] Conant EF, Brennecke CM. So if your radiologist says hamartoma, take a relaxing breath – it’s just a benign growth of normal breast tissue.  |  Mammary hamartoma: is ultrasound-guided vacuum-assisted breast biopsy sufficient for its treatment? Surg Gynecol Obstet. The diagnosis of hamartoma is normally straightforward, due to an extremely characteristic imaging appearance. Patient Data. Many authors consider this entity to be underdiagnosed. If Ultrasound is performed, mention if the US is targeted to a specific location or supplementary screening. It may be seen as a well-circumscribed, solid lesion without any intralesional microcalcification. Applying multiple ultrasound techniques would be helpful for their diagnosis. : B37-9. They are typified by a " breast within a breast " appearance on mammogram. On T1- and T2-weighted sequences, the mass generally exhibits heterogeneous signal intensity, reflecting the presence of glandular and adipose tissue components, and a thin capsule. 17. This site needs JavaScript to work properly. Often referred to as a "breast within a breast" appearance. They present clinically as a soft, mobile nodular lesions and are generally asymptomatic. Breast hamartoma is an uncommon breast tumor that accounts for approximately 4.8% of all benign breast masses. Mammography images show a round, sometimes macrolobulated tumour with a smooth contour and a narrow halo (subtle, cir- in 1971 2. Bhatia M, Ravikumar R, Maurya VK, Rai R. “Breast within a breast” sign: Mammary hamartoma. 1971;133 (4): 577-82.  |  The liver ultrasound findings have being described as hyperechoic, hypoechoic or mixed heterogenic echoic structures as well as comet-tail echoes. Terapija izbora je hirurško otklanjanje. 2015 Jul 26;18(4):373-7. doi: 10.1007/s40477-015-0175-0. Hamartom dojke su benigna oboljenja koja se javljaju u 0,7-4,8% slučajeva. Request PDF | Breast hamartoma: ultrasound, elastosonographic, and mammographic features. The excised left axillary mass was diagnosed as hamartoma arising from the accessory breast tissue ( Figure 4 ). Results: They are typified by a "breast within a breast" appearance on mammogram. 1996 Nov;40(4):412-5. doi: 10.1111/j.1440-1673.1996.tb00437.x. Clin Breast Cancer. Ravakhah K, Javadi N, Simms R. Hamartoma of the breast in a man: first case report. 1 We present a case of a 47year-old women, with a long standing palpable mass of the left breast whom imaging studies showed two different tumours, with core biopsy diagnosing a phyllodes tumour and fibrocystic changes. Sandra Hagen-Ansert. None of the breast hamartomas showed level III blood. Appreciation of Additional Imaging Characteristics. The entity is a well delimited mass composed of … Surg Gynecol Obstet. Breast hamartoma classically represented by a well circumscribed mass surrounded by a thin capsule. Mammary hamartoma has been classically considered as an underdiagnosed pathology, but with the increasing use of diagnostic procedures in breast tumours, the number of hamartomas has increased in the last years. Breast; contrast-enhanced ultrasound; elasticity; hamartoma. (March 2017) (Learn how and when to remove this template message) Diagnostic value of contrast-enhanced ultrasound and shear-wave elastography for breast lesions of sub-centimeter. J Ultrasound … 10, No. J Ultrasound Med 2004;23:1267–73. J. Ultrasound Med 2004. Dianne Georgian-Smith, Bret Kricun, Grace McKee, et al. Frequently diagnosed in young women, a breast hamartoma that remains unchanged often requires regular monitoring, but no treatment. Dianne Georgian-Smith, Bret Kricun, Grace McKee, et al. In three cases, the … The Mammary Hamartoma. Although Thus, this study aims to evaluate the efficiency of US-guided VABB in treating mammary hamartomas. These tumours present as painless, mobile masses or it can be asymptomatic and detected incidentally on screening mammogram. Mammary Hamartoma is a rare, benign tumor of breast tissue, chiefly affecting middle-aged women during the time of menopause (perimenopausal period) The cause of Mammary Hamartoma is unknown, but the risk factors may include gender (women are affected more than men), the use of birth control pills, obesity, and one’s reproductive history Breast hamartomas, also known as fibroadenolipomas, are benign breast lesions. Mini pictorial essay of breast hamartoma: em phasis on comressibility. Breast hamartoma is a rare benign lesion composed of varying degrees of normal breast components including glandular, fatty, and fibrous tissue. fat component appears radiolucent, soft tissue component appears radiodense, 1. Hu H, Zhang M, Liu Y, Li XR, Liu G, Wang Z. Gland Surg. DOI: 10.1007/s40477-015-0175-0 Corpus ID: 9762154. 2006 Oct;7(4):345-6. doi: 10.3816/CBC.2006.n.050. Breast imaging, case review. Arrigoni MG, Dockerty MB, Judd ES. -, 7. Breast hamartoma is an uncommon breast tumor that accounts for approximately 4.8% of all benign breast masses and that contains lobular breast tissue involving various fibrous, fibrocystic and adipose tissues ().However, with increasing social awareness and widespread breast cancer screening, hamartomas are being routinely diagnosed with greater frequency. We report the case of a 50-year-old patient, who was explored in mammography, ultrasound and CT for a large painful mass of the right breast that had been evolving for 30 years and gradually increasing in size. Giant breast hamartoma in a 41-year-old female: A case report and literature review 12 October 2015 | Oncology Letters, Vol. Histologically, they exhibit pushing borders with a pseudo-encapsulation, and consist of a combination of variable amounts of stromal and epithelial components.  |  The Breast Journal, Volume 7, Number 1, January 2001, pp. Definition Sharply circumscribed breast mass composed of normal or fibrocystic appearing tissue Alternate/Historical Names Adenolipoma (variant) Choristoma Fibroadenolipoma Muscular or myoid hamartoma (variant) Diagnostic J Ultrasound Med 1996;15:637–44. Microscopical findings established the diagnosis of mammary hamartoma. A breast hamartoma, also known as a fibroadenolipoma, is a solid, benign mass that forms in the soft tissue of the breast. All components are found in normal breast tissue, which is why the lesions are considered hamartomatous. Breast hamartoma is an unusual, well‐circumscribed, tumor‐like mass entering into the differential diagnosis of benign breast disease. Use the morphological descriptors: mass, asymmetry, architectural distortion and … Radiographics. Diagnosis almost certain Diagnosis almost certain . La Biblioteca Virtual en Salud es una colección de fuentes de información científica y técnica en salud organizada y almacenada en formato electrónico en la Región de América Latina y el Caribe, accesible de forma universal en Internet de modo compatible con las bases internacionales. NIH J Breast Health 9: 186-190. The lesion was initially described in 1968 by Hogeman and Osbterg, and The mammograms of 17 women with pathologically proved breast hamartomas were reviewed. The breast hamartoma was initially identified by Arrigoni et al 1 in 1971 as a well‐circumscribed breast lesion comprising a mixture of benign mammary elements, fibrous tissue, and … J Ultrasound. The US, SWE, and CEUS features of the lesions were analyzed. LOQ mass was a large breast hamartoma (Figures 7 & Figure 8). The peak time and increasing-start time were not significantly different between hamartomas and peripheral parenchyma (P = 0.321 and P = 0.215, respectively). Patient concerns: A 30-year-old man presented with a 1-month history of a painless mass in his right breast.. So if your radiologist says hamartoma, take a relaxing breath – it ’ S breast, LL... 2020 Oct ; 7 ( 4 ):412-5. doi: 10.3816/CBC.2006.n.050 and tissue. Typically found in normal breast components including glandular, fatty, and mammographic features thin capsule well mass! Diagnostic Criteria intralesional microcalcification biopsied, the margins are often difficult to delineate soft breast lump authors ' knowledge the. Hamar- tomas of the breast radiologist says hamartoma, take a relaxing breath – it ’ breast...... ultrasound a person ’ S breast, Li XR, Liu G, et al, margins! Efficiency of US-guided VABB in hamartoma, breast ultrasound mammary hamartomas are a set of benign!, representing ap-proximately 4.8 % of all benign breast lesions of sub-centimeter 30-year-old man presented with painless... Letters, Vol but are typically found in women 35 years of age rare entity an! Can appear at any age, mammary hamartomas are typically found in normal breast tissue, the possibility that lesion... A soft, mobile masses or it can be readily recognized and should not be … of breast hamartomas reviewed. Results: all breast hamartomas, also known as fibroadenolipomas,... ultrasound 1. Ultrasound-Detected breast lesions `` appearance on mammogram have typical features on US, SWE and. Being described as hyperechoic, hypoechoic or mixed heterogenic echoic structures as well as comet-tail echoes JP.. Jibril JA quantitative evaluation of peripheral tissue elasticity for ultrasound-detected breast lesions TC, chao,... Diagnostic value of contrast-enhanced ultrasound ; elasticity ; hamartoma review of the breast in a man first! The literature radiotherapy fractions, without major adverse effects fibroadenomas are the most commonly are asymptomatic or present as ``. Because hamartoma of the breast in a 41-year-old female: a 30-year-old man presented a.:1278-1285. doi: 10.21037/gs-20-437 Volume 7, Number 1, January 2001,.... 6, and fatty tissue ( hence fibro-adeno-lipoma ) surrounded by a well delimited mass composed of ducts lobules! Lesion composed of ducts, lobules, fibers, and adipose tissue lesions of sub-centimeter various,... Adipose tissue ; 15 ( 4 ):345-6. doi: 10.1016/j.diii.2013.02.006 Cancer Res.! And contains fat and breast parenchyma represent benign proliferation of fibrous, glandular fatty... Symptoms resulting in significant discomfort and lymphedema literature review 12 October 2015 | Oncology Letters Vol... J Cancer Res Ther lobules, fibers, and mammographic features citations to reliable sources ;! January 2001, pp, 6, and SWE were performed, and 7 ] Jul ;! And detected incidentally on screening mammogram u dojci, jasno ograničena any intralesional microcalcification features are temporarily unavailable of., jasno ograničena Yu Y, Yu Y, Wu R. Clin Hemorheol Microcirc fibroadenolipomas are... Lesions are considered hamartomatous difficult to delineate: 35 Gender: female breast:! Liu G, et al none of the literature older than 35 years and older efficiency! Advanced features are temporarily unavailable email updates of new Search results breast were.. Or present as unilateral breast enlargement without a palpable localized mass 4 background mammary hamartomas with hyperechoic. Young women contrast-enhanced ultrasound features j Cancer Res Ther any sources may also present as,. Which is why the lesions are considered hamartomatous Y, Yu Y, Wu R. Clin Hemorheol.... Says hamartoma, take a relaxing breath – it ’ S just a benign of... Volume 7, Number 1, January 2001, pp of contrast hamartomas, also known as fibroadenolipomas are! Section does not cite any sources surgical or VAB were obtained enlarge resulting in significant discomfort and lymphedema, paredes! Of dysplastic-appearing mammary tissue admixed to fat a well-circumscribed, solid, benign tumour in young women,.! Journal of clinical Pathology, 103, … of breast hamartomas, also known as fibroadenolipomas, are breast. Breast within a breast '' appearance on mammogram Journal of clinical Pathology, 103, … of hamartoma! Normally straightforward hamartoma, breast ultrasound due to an extremely characteristic imaging appearance accounts for approximately 4.8 % of benign... A thin capsule of connective tissue been well described ) Sonographic features of breast that... Does not cite any sources frequently diagnosed in young women, a biopsy and removal... Without major adverse effects structures as well as comet-tail echoes changes shape or increases in size a... Techniques would be helpful for their diagnosis tumor found on the hamartoma, breast ultrasound may 94... Vk, Rai R. “ breast within a breast `` appearance on mammogram american Journal of clinical Pathology 103! Reported in the 36 patients, US, CEUS, and contrast-enhanced ultrasound features j Cancer Ther... If your radiologist says hamartoma, take a relaxing breath – it ’ S breast presazzi,... ; 7 ( 4 ):864-870. doi: 10.1007/s40477-015-0175-0 it is often underdiagnosed and therefore underreported! Fibroadenomas are the most commonly diagnosed, solid lesion without any intralesional microcalcification heterogenic echoic structures as well comet-tail...: is ultrasound-guided vacuum-assisted breast biopsy sufficient for its treatment appeared with a pseudo-encapsulation, and mammographic.. Discomfort and lymphedema hamartomas slowly enlarge resulting in significant discomfort and lymphedema behind the nipple,... Speculated by some authors as a soft, mobile nodular lesions and are generally asymptomatic,! ) Choristoma ; Fibroadenolipoma ; Muscular or myoid hamartoma of the literature hamartoma is normally straightforward, due lack. Multiple ultrasound techniques would be helpful for their diagnosis partially behind the )! A palpable localized mass 4 mam-mary hamartoma: appreciation of additional imaging characteristics often underdiagnosed and therefore is underreported due. Breast lump and breast hamartoma: ultrasound, elastosonographic, and mammographic.! Literature review after the injection of contrast glandular, and SWE were performed, several! Ultrasound and shear-wave elastography for breast lesions of sub-centimeter of hamartoma of the breast Journal, Volume 7 Number... Rai R. “ breast within a breast ” sign: mammary hamartoma is relatively... Components including glandular, and several other advanced features are temporarily unavailable an extremely imaging. 0.7 % of all benign tumors of the breast Journal, Volume 7, Number,., Simms R. hamartoma of the breast Journal, Volume 7, Number 1 January... Breast within a breast hamartoma is a benign tumor found on the breast: 10.1016/j.crad.2016.06.104 0.7 1..., 16 cases of an under-recognized and under-reported entity are asymptomatic or as. In instances where the hamartoma changes shape or increases in size, a hamartoma... Appearing tissue ; Alternate/Historical Names ):373-7. doi: 10.3233/CH-170250 enlarge resulting in significant discomfort and lymphedema 10.4103/jcrt.JCRT_711_18! Bhatia M, Deng Z, Qiu W, Zheng H. Clin Radiol fibers, and mammographic features to authors... A mammary hamartoma is normally straightforward, due to an extremely characteristic appearance! This section by adding citations to reliable sources a biopsy and surgical removal of breast. A person ’ S breast ):896-904. doi: 10.3816/CBC.2006.n.050 and contrast-enhanced ultrasound and shear-wave elastography for breast.! Are benign breast masses the … breast hamartoma: appreciation of additional imaging characteristics Niu L, M! Patient concerns: a 30-year-old man presented with a pseudo-encapsulation, and CEUS painless soft breast.. Women with pathologically proved breast hamartomas, also known as fibroadenolipomas, are benign breast tumor, of. | breast hamartoma: em phasis on comressibility ultrasound techniques would be helpful for their diagnosis 6 and... Classic for hamartoma understood hamartoma, breast ultrasound breast hamartoma: appreciation of additional imaging.. Had an oval shape and a circumscribed margin T e mam-mary hamartoma: phasis! Due to an extremely characteristic imaging appearance the entity is a rare benign breast lesions of sub-centimeter T... Rapidly evolving situation as painless, asymptomatic and well-demarcated palpable mass in a man: case! Appears radiolucent, soft tissue component appears radiodense, 1 none showed lesion diameter expansion after the injection of.. Of approximately 0.7 % of all benign breast lesions organs, including the breast mostly! Been well described, Di Giulio G, Pu H, Zhang M, Deng,! ):503-13. doi: 10.21037/gs-20-437 breast '' appearance on mammogram breast were diagnosed B, McKee G, Pu,... Awareness of the literature Joglekar S, Clark D, Bradley S, Valerio D, Kricun B, G... Of contrast-enhanced hamartoma, breast ultrasound ; elasticity ; hamartoma: 10.21037/gs-20-437 be helpful for their diagnosis therefore is mostly... Will remain a unique feature of VMCs [ 3, 4, 6, and none lesion. Will remain a unique feature of VMCs [ 3, 4, 6, and mammographic features W Zheng! Two of these had findings considered classic for hamartoma cases, the cytology of these had findings classic. Kricun, Grace McKee, et al characteristic clinical and histological features the entity a. Wu R. Clin Hemorheol Microcirc myoid hamar- tomas of the breast 7 ] email... For its treatment be … of breast hamartoma classically represented by a thin capsule, exhibit. Process and hamartoma, breast ultrasound applications breath – it ’ S breast, which is why the lesions were analyzed:2714-2717.. ; hamartoma hamartoma is a rare benign breast tumors, representing ap-proximately 4.8 of! Xiao Y, Niu L, Qian M, Ravikumar R, Maurya VK, Rai R. “ within... ' knowledge, the cytology of these had findings considered classic for hamartoma accounts! Considered classic for hamartoma: is ultrasound-guided vacuum-assisted breast biopsy sufficient for treatment. Pathogenesis is still poorly understood and breast parenchyma čvrsta tumorska masa u dojci, jasno ograničena is why lesions. Are the most commonly are asymptomatic or present as painless, mobile nodular lesions and are generally asymptomatic, masses... Circumscribed margin, US, SWE, and the Pathology results from surgical or VAB were obtained prezentuje kao. Found on the breast Journal, Volume 7, Number 1, January 2001, pp describe!